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Distinct Phenotypes Induced by Three Degrees of Transverse Aortic Constriction in Mice
Transverse aortic constriction (TAC) is a well-established model of pressure overload-induced cardiac hypertrophy and failure in mice. The degree of constriction “tightness” dictates the TAC severity and is determined by the gauge (G) of needle used. Though many reports use the TAC model, few studie...
Autores principales: | Richards, Daniel A., Aronovitz, Mark J., Calamaras, Timothy D., Tam, Kelly, Martin, Gregory L., Liu, Peiwen, Bowditch, Heather K., Zhang, Phyllis, Huggins, Gordon S., Blanton, Robert M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458135/ https://www.ncbi.nlm.nih.gov/pubmed/30971724 http://dx.doi.org/10.1038/s41598-019-42209-7 |
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