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Extracellular Vesicles from Apoptotic Cells Promote TGFβ Production in Macrophages and Suppress Experimental Colitis

The clearance of apoptotic cells is an essential process to maintain homeostasis of immune system, which is regulated by immunoregulatory cytokines such as TGFβ. We show here that Extracellular Vesicles (EVs) were highly released from apoptotic cells, and contributed to macrophage production of TGFβ...

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Detalles Bibliográficos
Autores principales: Chen, Hua, Kasagi, Shimpei, Chia, Cheryl, Zhang, Dunfang, Tu, Eric, Wu, Ruiqing, Zanvit, Peter, Goldberg, Nathan, Jin, Wenwen, Chen, WanJun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458171/
https://www.ncbi.nlm.nih.gov/pubmed/30971739
http://dx.doi.org/10.1038/s41598-019-42063-7