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Perovskite nickelates as bio-electronic interfaces
Functional interfaces between electronics and biological matter are essential to diverse fields including health sciences and bio-engineering. Here, we report the discovery of spontaneous (no external energy input) hydrogen transfer from biological glucose reactions into SmNiO(3), an archetypal pero...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458181/ https://www.ncbi.nlm.nih.gov/pubmed/30971693 http://dx.doi.org/10.1038/s41467-019-09660-6 |
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author | Zhang, Hai-Tian Zuo, Fan Li, Feiran Chan, Henry Wu, Qiuyu Zhang, Zhan Narayanan, Badri Ramadoss, Koushik Chakraborty, Indranil Saha, Gobinda Kamath, Ganesh Roy, Kaushik Zhou, Hua Chubykin, Alexander A. Sankaranarayanan, Subramanian K. R. S. Choi, Jong Hyun Ramanathan, Shriram |
author_facet | Zhang, Hai-Tian Zuo, Fan Li, Feiran Chan, Henry Wu, Qiuyu Zhang, Zhan Narayanan, Badri Ramadoss, Koushik Chakraborty, Indranil Saha, Gobinda Kamath, Ganesh Roy, Kaushik Zhou, Hua Chubykin, Alexander A. Sankaranarayanan, Subramanian K. R. S. Choi, Jong Hyun Ramanathan, Shriram |
author_sort | Zhang, Hai-Tian |
collection | PubMed |
description | Functional interfaces between electronics and biological matter are essential to diverse fields including health sciences and bio-engineering. Here, we report the discovery of spontaneous (no external energy input) hydrogen transfer from biological glucose reactions into SmNiO(3), an archetypal perovskite quantum material. The enzymatic oxidation of glucose is monitored down to ~5 × 10(−16) M concentration via hydrogen transfer to the nickelate lattice. The hydrogen atoms donate electrons to the Ni d orbital and induce electron localization through strong electron correlations. By enzyme specific modification, spontaneous transfer of hydrogen from the neurotransmitter dopamine can be monitored in physiological media. We then directly interface an acute mouse brain slice onto the nickelate devices and demonstrate measurement of neurotransmitter release upon electrical stimulation of the striatum region. These results open up avenues for use of emergent physics present in quantum materials in trace detection and conveyance of bio-matter, bio-chemical sciences, and brain-machine interfaces. |
format | Online Article Text |
id | pubmed-6458181 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-64581812019-04-12 Perovskite nickelates as bio-electronic interfaces Zhang, Hai-Tian Zuo, Fan Li, Feiran Chan, Henry Wu, Qiuyu Zhang, Zhan Narayanan, Badri Ramadoss, Koushik Chakraborty, Indranil Saha, Gobinda Kamath, Ganesh Roy, Kaushik Zhou, Hua Chubykin, Alexander A. Sankaranarayanan, Subramanian K. R. S. Choi, Jong Hyun Ramanathan, Shriram Nat Commun Article Functional interfaces between electronics and biological matter are essential to diverse fields including health sciences and bio-engineering. Here, we report the discovery of spontaneous (no external energy input) hydrogen transfer from biological glucose reactions into SmNiO(3), an archetypal perovskite quantum material. The enzymatic oxidation of glucose is monitored down to ~5 × 10(−16) M concentration via hydrogen transfer to the nickelate lattice. The hydrogen atoms donate electrons to the Ni d orbital and induce electron localization through strong electron correlations. By enzyme specific modification, spontaneous transfer of hydrogen from the neurotransmitter dopamine can be monitored in physiological media. We then directly interface an acute mouse brain slice onto the nickelate devices and demonstrate measurement of neurotransmitter release upon electrical stimulation of the striatum region. These results open up avenues for use of emergent physics present in quantum materials in trace detection and conveyance of bio-matter, bio-chemical sciences, and brain-machine interfaces. Nature Publishing Group UK 2019-04-10 /pmc/articles/PMC6458181/ /pubmed/30971693 http://dx.doi.org/10.1038/s41467-019-09660-6 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Zhang, Hai-Tian Zuo, Fan Li, Feiran Chan, Henry Wu, Qiuyu Zhang, Zhan Narayanan, Badri Ramadoss, Koushik Chakraborty, Indranil Saha, Gobinda Kamath, Ganesh Roy, Kaushik Zhou, Hua Chubykin, Alexander A. Sankaranarayanan, Subramanian K. R. S. Choi, Jong Hyun Ramanathan, Shriram Perovskite nickelates as bio-electronic interfaces |
title | Perovskite nickelates as bio-electronic interfaces |
title_full | Perovskite nickelates as bio-electronic interfaces |
title_fullStr | Perovskite nickelates as bio-electronic interfaces |
title_full_unstemmed | Perovskite nickelates as bio-electronic interfaces |
title_short | Perovskite nickelates as bio-electronic interfaces |
title_sort | perovskite nickelates as bio-electronic interfaces |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458181/ https://www.ncbi.nlm.nih.gov/pubmed/30971693 http://dx.doi.org/10.1038/s41467-019-09660-6 |
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