Cargando…

Plasma Heme Scavengers Alpha-1-Microglobulin and Hemopexin as Biomarkers in High-Risk Pregnancies

Women with established preeclampsia (PE) have increased plasma concentration of free fetal hemoglobin. We measured two hemoglobin scavenger system proteins, hemopexin (Hpx) and alpha-1-microglobulin (A1M) in maternal plasma using enzyme-linked immunosorbent assay during the late second trimester of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kalapotharakos, Grigorios, Murtoniemi, Katja, Åkerström, Bo, Hämäläinen, Esa, Kajantie, Eero, Räikkönen, Katri, Villa, Pia, Laivuori, Hannele, Hansson, Stefan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458234/ https://www.ncbi.nlm.nih.gov/pubmed/31019465 http://dx.doi.org/10.3389/fphys.2019.00300

Ejemplares similares

Longitudinal changes in plasma hemopexin and alpha-1-microglobulin concentrations in women with and without clinical risk factors for pre-eclampsia
por: Murtoniemi, Katja, et al.
Publicado: (2019)

Hemopexin and α(1)-microglobulin heme scavengers with differential involvement in preeclampsia and fetal growth restriction
por: Youssef, Lina, et al.
Publicado: (2020)

Prediction of pre-eclampsia and its subtypes in high-risk cohort: hyperglycosylated human chorionic gonadotropin in multivariate models
por: Murtoniemi, Katja, et al.
Publicado: (2018)

Vasoactive agents for the prediction of early- and late-onset preeclampsia in a high-risk cohort
por: Villa, Pia M, et al.
Publicado: (2013)

Maternal Prenatal Positive Affect, Depressive and Anxiety Symptoms and Birth Outcomes: The PREDO Study
por: Pesonen, Anu-Katriina, et al.
Publicado: (2016)

Maternal early-pregnancy body mass index-associated metabolomic component and mental and behavioral disorders in children
por: Girchenko, Polina, et al.
Publicado: (2022)

Longitudinal Metabolic Profiling of Maternal Obesity, Gestational Diabetes, and Hypertensive Pregnancy Disorders
por: Kivelä, Jemina, et al.
Publicado: (2021)

Metabolomic Profiles of Nonobese and Obese Women With Gestational Diabetes
por: Sormunen-Harju, Heidi, et al.
Publicado: (2023)

Cluster analysis to estimate the risk of preeclampsia in the high-risk Prediction and Prevention of Preeclampsia and Intrauterine Growth Restriction (PREDO) study
por: Villa, Pia M., et al.
Publicado: (2017)

Maternal depressive symptoms during and after pregnancy are associated with attention-deficit/hyperactivity disorder symptoms in their 3- to 6-year-old children
por: Wolford, Elina, et al.
Publicado: (2017)

Infant regulatory behavior problems during first month of life and neurobehavioral outcomes in early childhood
por: Toffol, Elena, et al.
Publicado: (2018)

Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases
por: Canesin, Giacomo, et al.
Publicado: (2020)

Maternal postpartum depressive symptoms partially mediate the association between preterm birth and mental and behavioral disorders in children
por: Girchenko, Polina, et al.
Publicado: (2022)

Placental Morphology Is Associated with Maternal Depressive Symptoms during Pregnancy and Toddler Psychiatric Problems
por: Lahti-Pulkkinen, Marius, et al.
Publicado: (2018)

A polyepigenetic glucocorticoid exposure score at birth and childhood mental and behavioral disorders
por: Suarez, Anna, et al.
Publicado: (2020)

Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth
por: Girchenko, Polina, et al.
Publicado: (2017)

Characterization of heme binding to recombinant α(1)-microglobulin
por: Karnaukhova, Elena, et al.
Publicado: (2014)

The heme and radical scavenger α(1)-microglobulin (A1M) confers early protection of the immature brain following preterm intraventricular hemorrhage
por: Romantsik, Olga, et al.
Publicado: (2019)

Alpha-1 microglobulin as a potential therapeutic candidate for treatment of hypertension and oxidative stress in the STOX1 preeclampsia mouse model
por: Erlandsson, Lena, et al.
Publicado: (2019)

Human Plasma and Recombinant Hemopexins: Heme Binding Revisited
por: Karnaukhova, Elena, et al.
Publicado: (2021)

Maternal exposure to childhood maltreatment and mental and behavioral disorders in children
por: Airikka, Aino, et al.
Publicado: (2022)

Hemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contenders
por: Smith, Ann, et al.
Publicado: (2015)

α(1)-Microglobulin (A1M) Protects Human Proximal Tubule Epithelial Cells from Heme-Induced Damage In Vitro
por: Kristiansson, Amanda, et al.
Publicado: (2020)

Spatial transcriptome data from coronal mouse brain sections after striatal injection of heme and heme-hemopexin
por: Akeret, Kevin, et al.
Publicado: (2022)

Associations Between Maternal Antenatal Corticosteroid Treatment and Psychological Developmental and Neurosensory Disorders in Children
por: Räikkönen, Katri, et al.
Publicado: (2022)

Antenatal corticosteroid treatment and infectious diseases in children: a nationwide observational study
por: Räikkönen, Katri, et al.
Publicado: (2023)

What Is Next in This “Age” of Heme-Driven Pathology and Protection by Hemopexin? An Update and Links with Iron †
por: Montecinos, Luis, et al.
Publicado: (2019)

Hemopexin and Cancer
por: Fiorito, Veronica, et al.
Publicado: (2022)

Characteristics of epigenetic aging across gestational and perinatal tissues
por: Dieckmann, Linda, et al.
Publicado: (2021)

Pregnant alpha-1-microglobulin (A1M) knockout mice exhibit features of kidney and placental damage, hemodynamic changes and intrauterine growth restriction
por: Aleksenko, Larysa, et al.
Publicado: (2020)

Cohort profile: the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC)
por: Jääskeläinen, Tiina, et al.
Publicado: (2016)

Kidney Protection with the Radical Scavenger α(1)-Microglobulin (A1M) during Peptide Receptor Radionuclide and Radioligand Therapy
por: Kristiansson, Amanda, et al.
Publicado: (2021)

Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing
por: Czamara, Darina, et al.
Publicado: (2022)

Searching for a paternal phenotype for preeclampsia
por: Jaatinen, Noora, et al.
Publicado: (2022)

A1M/α(1)-microglobulin is proteolytically activated by myeloperoxidase, binds its heme group and inhibits low density lipoprotein oxidation
por: Cederlund, Martin, et al.
Publicado: (2015)

Alterations in Systemic Extracellular Heme and Hemopexin Are Associated With Adverse Clinical Outcomes in Ugandan Children With Severe Malaria
por: Elphinstone, Robyn E., et al.
Publicado: (2016)

A1M/α(1)-Microglobulin Protects from Heme-Induced Placental and Renal Damage in a Pregnant Sheep Model of Preeclampsia
por: Wester-Rosenlöf, Lena, et al.
Publicado: (2014)

Ferryl Hemoglobin and Heme Induce A(1)-Microglobulin in Hemorrhaged Atherosclerotic Lesions with Inhibitory Function against Hemoglobin and Lipid Oxidation
por: Pethő, Dávid, et al.
Publicado: (2021)

An Obesity-Related FTO Variant and the Risk of Preeclampsia in a Finnish Study Population
por: Klemetti, Miira, et al.
Publicado: (2011)

Erratum to “An Obesity-Related FTO Variant and the Risk of Preeclampsia in a Finnish Study Population”
por: Klemetti, Miira, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_m1vn9fc6lj0ea5n11l83c03u66