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2D Visualization of the Psoriasis Transcriptome Fails to Support the Existence of Dual-Secreting IL-17A/IL-22 Th17 T Cells

The present paradigm of psoriasis pathogenesis revolves around the IL-23/IL-17A axis. Dual-secreting Th17 T cells presumably are the predominant sources of the psoriasis phenotype-driving cytokines, IL-17A and IL-22. We thus conducted a meta-analysis of independently acquired RNA-seq psoriasis datas...

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Detalles Bibliográficos
Autores principales: Le, Stephanie T., Merleev, Alexander A., Luxardi, Guillaume, Shimoda, Michiko, Adamopoulos, Iannis E., Tsoi, Lam C., Wang, Jenny Z., Alexanian, Claire, Raychaudhuri, Siba P., Hwang, Samuel T., Gudjonsson, Johann, Marusina, Alina I., Maverakis, Emanual
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458264/
https://www.ncbi.nlm.nih.gov/pubmed/31019502
http://dx.doi.org/10.3389/fimmu.2019.00589

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