Cargando…

The iNOS Activity During an Immune Response Controls the CNS Pathology in Experimental Autoimmune Encephalomyelitis

Inducible nitric oxide synthase (iNOS) plays a critical role in the regulation of multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE). Previous studies have shown that iNOS plays pathogenic as well as regulatory roles in MS and EAE. However, how does iNOS alters the pathophys...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sonar, Sandip Ashok, Lal, Girdhari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458273/ https://www.ncbi.nlm.nih.gov/pubmed/31019516 http://dx.doi.org/10.3389/fimmu.2019.00710

Ejemplares similares

Differentiation and Transmigration of CD4 T Cells in Neuroinflammation and Autoimmunity
por: Sonar, Sandip Ashok, et al.
Publicado: (2017)

Role of Tumor Necrosis Factor Superfamily in Neuroinflammation and Autoimmunity
por: Sonar, Sandip, et al.
Publicado: (2015)

Deletion of UCP2 in iNOS Deficient Mice Reduces the Severity of the Disease during Experimental Autoimmune Encephalomyelitis
por: Aheng, Caroline, et al.
Publicado: (2011)

Sinomenine reduces iNOS expression via inhibiting the T-bet IFN-γ pathway in experimental autoimmune encephalomyelitis in rats
por: Gu, Bingjie, et al.
Publicado: (2012)

iNOS Activity Is Required for the Therapeutic Effect of Mesenchymal Stem Cells in Experimental Systemic Sclerosis
por: Maria, Alexandre T. J., et al.
Publicado: (2018)

Natural killer T cell activation increases iNOS(+)CD206(-) M1 macrophage and controls the growth of solid tumor
por: Paul, Sourav, et al.
Publicado: (2019)

Diazepam Impairs Innate and Adaptive Immune Responses and Ameliorates Experimental Autoimmune Encephalomyelitis
por: Falcón, Cristian R., et al.
Publicado: (2021)

Obesity-Induced Coronary Microvascular Disease Is Prevented by iNOS Deletion and Reversed by iNOS Inhibition
por: Shah, Soham A., et al.
Publicado: (2023)

IFN-γ–STAT1–iNOS Induces Myeloid Progenitors to Acquire Immunosuppressive Activity
por: Yang, Shu-Han, et al.
Publicado: (2017)

Matrix metalloproteinase-7 facilitates immune access to the CNS in experimental autoimmune encephalomyelitis
por: Buhler, Lillian A, et al.
Publicado: (2009)

Cholinergic System and Its Therapeutic Importance in Inflammation and Autoimmunity
por: Halder, Namrita, et al.
Publicado: (2021)

The dual role of iNOS in cancer()
por: Vannini, Federica, et al.
Publicado: (2015)

The Regulatory Function of CCR9(+) Dendritic Cells in Inflammation and Autoimmunity
por: Pathak, Manisha, et al.
Publicado: (2020)

Regulation of iNOS on Immune Cells and Its Role in Diseases
por: Xue, Qingjie, et al.
Publicado: (2018)

Individual in vivo Profiles of Microglia Polarization After Stroke, Represented by the Genes iNOS and Ym1
por: Collmann, Franziska M., et al.
Publicado: (2019)

Dengue induces iNOS expression and nitric oxide synthesis in platelets through IL-1R
por: Pinheiro, Mariana Brandi Mendonça, et al.
Publicado: (2022)

Immune Thymic Profile of the MOG-Induced Experimental Autoimmune Encephalomyelitis Mouse Model
por: das Neves, Sofia P., et al.
Publicado: (2018)

Brain function in iNOS knock out or iNOS inhibited (l-NIL) mice under endotoxic shock
por: Schweighöfer, Hanna, et al.
Publicado: (2014)

HDAC6 Mediates Macrophage iNOS Expression and Excessive Nitric Oxide Production in the Blood During Endotoxemia
por: Wang, Yan, et al.
Publicado: (2020)

The expressions of AMACR and iNOS in prostate adenocarcinomas
por: Ozgur, Tumay, et al.
Publicado: (2013)

Targeting iNOS to increase efficacy of immunotherapies
por: Ekmekcioglu, Suhendan, et al.
Publicado: (2017)

Age related immune modulation of experimental autoimmune encephalomyelitis in PINK1 knockout mice
por: Cossu, Davide, et al.
Publicado: (2022)

Podophyllotoxin and Rutin Modulate M1 (iNOS+) Macrophages and Mitigate Lethal Radiation (LR) Induced Inflammatory Responses in Mice
por: Nadella, Vinod, et al.
Publicado: (2019)

Gut Microbiota Interventions With Clostridium butyricum and Norfloxacin Modulate Immune Response in Experimental Autoimmune Encephalomyelitis Mice
por: Chen, Hao, et al.
Publicado: (2019)

Clozapine reduces infiltration into the CNS by targeting migration in experimental autoimmune encephalomyelitis
por: Robichon, Katharina, et al.
Publicado: (2020)

Central Nervous System Barriers Impact Distribution and Expression of iNOS and Arginase-1 in Infiltrating Macrophages During Neuroinflammation
por: Ivan, Daniela C., et al.
Publicado: (2021)

A B Cell-Driven Autoimmune Pathway Leading to Pathological Hallmarks of Progressive Multiple Sclerosis in the Marmoset Experimental Autoimmune Encephalomyelitis Model
por: ’t Hart, Bert A., et al.
Publicado: (2017)

Retraction: Podophyllotoxin and Rutin Modulate M1 (iNOS+) Macrophages and Mitigate Lethal Radiation (LR) Induced Inflammatory Responses in Mice
Publicado: (2022)

Clozapine Regulates Microglia and Is Effective in Chronic Experimental Autoimmune Encephalomyelitis
por: Ceylan, Ulaş, et al.
Publicado: (2021)

Parthenolide Suppresses T Helper 17 and Alleviates Experimental Autoimmune Encephalomyelitis
por: Zhang, Zhihui, et al.
Publicado: (2022)

iNOS polymorphism modulates iNOS/NO expression via impaired antioxidant and ROS content in P. vivax and P. falciparum infection
por: Kumar, Amod, et al.
Publicado: (2017)

Role of miRNAs in CD4 T cell plasticity during inflammation and tolerance
por: Sethi, Apoorva, et al.
Publicado: (2013)

Innate Activation of IFN-γ—iNOS Axis During Infection With Salmonella Represses the Ability of T Cells to Produce IL-2
por: Yadav, Jitender, et al.
Publicado: (2020)

IFNγ and iNOS-Mediated Alterations in the Bone Marrow and Thymus and Its Impact on Mycobacterium avium-Induced Thymic Atrophy
por: Barreira-Silva, Palmira, et al.
Publicado: (2021)

Upregulation of iNOS and phosphorylated eNOS in the implantation‐induced blastocysts of mice
por: Seki, Misato, et al.
Publicado: (2023)

Aging and Insulin Resistance: Just Say iNOS
por: Evans, Joseph L., et al.
Publicado: (2013)

T Follicular Helper-Like Cells Are Involved in the Pathogenesis of Experimental Autoimmune Encephalomyelitis
por: Guo, Jun, et al.
Publicado: (2018)

Role of Anti-Osteopontin Antibodies in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis
por: Clemente, Nausicaa, et al.
Publicado: (2017)

Tim-3 Relieves Experimental Autoimmune Encephalomyelitis by Suppressing MHC-II
por: Tang, Lili, et al.
Publicado: (2022)

RGC-32 Regulates Generation of Reactive Astrocytes in Experimental Autoimmune Encephalomyelitis
por: Tatomir, Alexandru, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7u2se1861ncgfvbpir1l7mo1vo