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SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player
Interleukin-1β (IL-1β) is a potent, pro-inflammatory cytokine of the innate immune system that plays an essential role in host defense against infection. However, elevated circulating levels of IL-1β can cause life-threatening systemic inflammation. Hence, mechanisms controlling IL-1β maturation and...
Autores principales: | Zakrzewicz, Anna, Richter, Katrin, Zakrzewicz, Dariusz, Siebers, Kathrin, Damm, Jelena, Agné, Alisa, Hecker, Andreas, McIntosh, J. Michael, Chamulitrat, Walee, Krasteva-Christ, Gabriela, Manzini, Ivan, Tikkanen, Ritva, Padberg, Winfried, Janciauskiene, Sabina, Grau, Veronika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458293/ https://www.ncbi.nlm.nih.gov/pubmed/31019507 http://dx.doi.org/10.3389/fimmu.2019.00664 |
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