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CSF glial biomarkers YKL40 and sTREM2 are associated with longitudinal volume and diffusivity changes in cognitively unimpaired individuals

Cerebrospinal fluid (CSF) YKL40 and sTREM2 are astroglial and microglial activity biomarkers, respectively. We assessed whether CSF YKL40 and sTREM2 baseline levels are associated with longitudinal brain volume and diffusivity changes in cognitively unimpaired adults. Two brain MRI scans of 36 parti...

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Detalles Bibliográficos
Autores principales:	Falcon, Carles, Monté-Rubio, Gemma C., Grau-Rivera, Oriol, Suárez-Calvet, Marc, Sánchez-Valle, Raquel, Rami, Lorena, Bosch, Beatriz, Haass, Christian, Gispert, Juan Domingo, Molinuevo, José Luis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458453/ https://www.ncbi.nlm.nih.gov/pubmed/30978656 http://dx.doi.org/10.1016/j.nicl.2019.101801

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