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PCC0208018 exerts antitumor effects by activating effector T cells

Poor prognosis is associated with melanoma due to immunosuppression profiles, suggesting that immune alterations have an important role in the occurrence, growth, and metastasis of melanoma. Here, we found that PCC0208018, a small-molecule compound, enhanced T cell proliferation and activation to re...

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Detalles Bibliográficos
Autores principales: Ge, Minmin, Hu, Zhengping, Chen, Xiao, Du, Guangying, Wang, Hongbo, Liu, Rumeng, Ye, Liang, Tian, Jingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458668/
https://www.ncbi.nlm.nih.gov/pubmed/30968715
http://dx.doi.org/10.1177/2058738419843366