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Moonstone: a novel natural language processing system for inferring social risk from clinical narratives

BACKGROUND: Social risk factors are important dimensions of health and are linked to access to care, quality of life, health outcomes and life expectancy. However, in the Electronic Health Record, data related to many social risk factors are primarily recorded in free-text clinical notes, rather tha...

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Autores principales: Conway, Mike, Keyhani, Salomeh, Christensen, Lee, South, Brett R., Vali, Marzieh, Walter, Louise C., Mowery, Danielle L., Abdelrahman, Samir, Chapman, Wendy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458709/
https://www.ncbi.nlm.nih.gov/pubmed/30975223
http://dx.doi.org/10.1186/s13326-019-0198-0
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author Conway, Mike
Keyhani, Salomeh
Christensen, Lee
South, Brett R.
Vali, Marzieh
Walter, Louise C.
Mowery, Danielle L.
Abdelrahman, Samir
Chapman, Wendy W.
author_facet Conway, Mike
Keyhani, Salomeh
Christensen, Lee
South, Brett R.
Vali, Marzieh
Walter, Louise C.
Mowery, Danielle L.
Abdelrahman, Samir
Chapman, Wendy W.
author_sort Conway, Mike
collection PubMed
description BACKGROUND: Social risk factors are important dimensions of health and are linked to access to care, quality of life, health outcomes and life expectancy. However, in the Electronic Health Record, data related to many social risk factors are primarily recorded in free-text clinical notes, rather than as more readily computable structured data, and hence cannot currently be easily incorporated into automated assessments of health. In this paper, we present Moonstone, a new, highly configurable rule-based clinical natural language processing system designed to automatically extract information that requires inferencing from clinical notes. Our initial use case for the tool is focused on the automatic extraction of social risk factor information — in this case, housing situation, living alone, and social support — from clinical notes. Nursing notes, social work notes, emergency room physician notes, primary care notes, hospital admission notes, and discharge summaries, all derived from the Veterans Health Administration, were used for algorithm development and evaluation. RESULTS: An evaluation of Moonstone demonstrated that the system is highly accurate in extracting and classifying the three variables of interest (housing situation, living alone, and social support). The system achieved positive predictive value (i.e. precision) scores ranging from 0.66 (homeless/marginally housed) to 0.98 (lives at home/not homeless), accuracy scores ranging from 0.63 (lives in facility) to 0.95 (lives alone), and sensitivity (i.e. recall) scores ranging from 0.75 (lives in facility) to 0.97 (lives alone). CONCLUSIONS: The Moonstone system is — to the best of our knowledge — the first freely available, open source natural language processing system designed to extract social risk factors from clinical text with good (lives in facility) to excellent (lives alone) performance. Although developed with the social risk factor identification task in mind, Moonstone provides a powerful tool to address a range of clinical natural language processing tasks, especially those tasks that require nuanced linguistic processing in conjunction with inference capabilities.
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spelling pubmed-64587092019-04-19 Moonstone: a novel natural language processing system for inferring social risk from clinical narratives Conway, Mike Keyhani, Salomeh Christensen, Lee South, Brett R. Vali, Marzieh Walter, Louise C. Mowery, Danielle L. Abdelrahman, Samir Chapman, Wendy W. J Biomed Semantics Software BACKGROUND: Social risk factors are important dimensions of health and are linked to access to care, quality of life, health outcomes and life expectancy. However, in the Electronic Health Record, data related to many social risk factors are primarily recorded in free-text clinical notes, rather than as more readily computable structured data, and hence cannot currently be easily incorporated into automated assessments of health. In this paper, we present Moonstone, a new, highly configurable rule-based clinical natural language processing system designed to automatically extract information that requires inferencing from clinical notes. Our initial use case for the tool is focused on the automatic extraction of social risk factor information — in this case, housing situation, living alone, and social support — from clinical notes. Nursing notes, social work notes, emergency room physician notes, primary care notes, hospital admission notes, and discharge summaries, all derived from the Veterans Health Administration, were used for algorithm development and evaluation. RESULTS: An evaluation of Moonstone demonstrated that the system is highly accurate in extracting and classifying the three variables of interest (housing situation, living alone, and social support). The system achieved positive predictive value (i.e. precision) scores ranging from 0.66 (homeless/marginally housed) to 0.98 (lives at home/not homeless), accuracy scores ranging from 0.63 (lives in facility) to 0.95 (lives alone), and sensitivity (i.e. recall) scores ranging from 0.75 (lives in facility) to 0.97 (lives alone). CONCLUSIONS: The Moonstone system is — to the best of our knowledge — the first freely available, open source natural language processing system designed to extract social risk factors from clinical text with good (lives in facility) to excellent (lives alone) performance. Although developed with the social risk factor identification task in mind, Moonstone provides a powerful tool to address a range of clinical natural language processing tasks, especially those tasks that require nuanced linguistic processing in conjunction with inference capabilities. BioMed Central 2019-04-11 /pmc/articles/PMC6458709/ /pubmed/30975223 http://dx.doi.org/10.1186/s13326-019-0198-0 Text en © The Author(s) 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Software
Conway, Mike
Keyhani, Salomeh
Christensen, Lee
South, Brett R.
Vali, Marzieh
Walter, Louise C.
Mowery, Danielle L.
Abdelrahman, Samir
Chapman, Wendy W.
Moonstone: a novel natural language processing system for inferring social risk from clinical narratives
title Moonstone: a novel natural language processing system for inferring social risk from clinical narratives
title_full Moonstone: a novel natural language processing system for inferring social risk from clinical narratives
title_fullStr Moonstone: a novel natural language processing system for inferring social risk from clinical narratives
title_full_unstemmed Moonstone: a novel natural language processing system for inferring social risk from clinical narratives
title_short Moonstone: a novel natural language processing system for inferring social risk from clinical narratives
title_sort moonstone: a novel natural language processing system for inferring social risk from clinical narratives
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458709/
https://www.ncbi.nlm.nih.gov/pubmed/30975223
http://dx.doi.org/10.1186/s13326-019-0198-0
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