Deletion of the KH1 Domain of Fmr1 Leads to Transcriptional Alterations and Attentional Deficits in Rats

Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by mutations in the FMR1 gene. It is a leading monogenic cause of autism spectrum disorder and inherited intellectual disability and is often comorbid with attention deficits. Most FXS cases are due to an expansion of CGG repeats leadi...

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Detalles Bibliográficos
Autores principales: Golden, Carla E M, Breen, Michael S, Koro, Lacin, Sonar, Sankalp, Niblo, Kristi, Browne, Andrew, Burlant, Natalie, Di Marino, Daniele, De Rubeis, Silvia, Baxter, Mark G, Buxbaum, Joseph D, Harony-Nicolas, Hala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458915/
https://www.ncbi.nlm.nih.gov/pubmed/30877790
http://dx.doi.org/10.1093/cercor/bhz029

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