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The HIV-1 Envelope Glycoprotein C3/V4 Region Defines a Prevalent Neutralization Epitope following Immunization
Despite recent progress in engineering native trimeric HIV-1 envelope glycoprotein (Env) mimics as vaccine candidates, Env trimers often induce vaccine-matched neutralizing antibody (NAb) responses. Understanding the specificities of autologous NAb responses and the underlying molecular mechanisms r...
Autores principales: | Lei, Lin, Yang, Yuhe R., Tran, Karen, Wang, Yimeng, Chiang, Chi-I, Ozorowski, Gabriel, Xiao, Yongli, Ward, Andrew B., Wyatt, Richard T., Li, Yuxing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458978/ https://www.ncbi.nlm.nih.gov/pubmed/30970260 http://dx.doi.org/10.1016/j.celrep.2019.03.039 |
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