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Understanding the Time Needed to Link to Care and Start ART in Seven HPTN 071 (PopART) Study Communities in Zambia and South Africa

To achieve UNAIDS 90:90:90 targets at population-level, knowledge of HIV status must be followed by timely linkage to care, initiation and maintenance of antiretroviral therapy (ART) for all people living with HIV (PLHIV). Interpreting quantitative patterns using qualitative data, we investigate tim...

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Autores principales: Seeley, Janet, Bond, Virginia, Yang, Blia, Floyd, Sian, MacLeod, David, Viljoen, Lario, Phiri, Mwelwa, Simuyaba, Melvin, Hoddinott, Graeme, Shanaube, Kwame, Bwalya, Chiti, de Villiers, Laing, Jennings, Karen, Mwanza, Margaret, Schaap, Ab, Dunbar, Rory, Sabapathy, Kalpana, Ayles, Helen, Bock, Peter, Hayes, Richard, Fidler, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458981/
https://www.ncbi.nlm.nih.gov/pubmed/30415432
http://dx.doi.org/10.1007/s10461-018-2335-7
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author Seeley, Janet
Bond, Virginia
Yang, Blia
Floyd, Sian
MacLeod, David
Viljoen, Lario
Phiri, Mwelwa
Simuyaba, Melvin
Hoddinott, Graeme
Shanaube, Kwame
Bwalya, Chiti
de Villiers, Laing
Jennings, Karen
Mwanza, Margaret
Schaap, Ab
Dunbar, Rory
Sabapathy, Kalpana
Ayles, Helen
Bock, Peter
Hayes, Richard
Fidler, Sarah
author_facet Seeley, Janet
Bond, Virginia
Yang, Blia
Floyd, Sian
MacLeod, David
Viljoen, Lario
Phiri, Mwelwa
Simuyaba, Melvin
Hoddinott, Graeme
Shanaube, Kwame
Bwalya, Chiti
de Villiers, Laing
Jennings, Karen
Mwanza, Margaret
Schaap, Ab
Dunbar, Rory
Sabapathy, Kalpana
Ayles, Helen
Bock, Peter
Hayes, Richard
Fidler, Sarah
author_sort Seeley, Janet
collection PubMed
description To achieve UNAIDS 90:90:90 targets at population-level, knowledge of HIV status must be followed by timely linkage to care, initiation and maintenance of antiretroviral therapy (ART) for all people living with HIV (PLHIV). Interpreting quantitative patterns using qualitative data, we investigate time taken to link to care and initiate ART amongst individuals aware of their HIV-status in high HIV-prevalence urban communities in the HPTN 071 (PopART) study, a community-randomised trial of a combination HIV prevention package, including universal testing and treatment, in 21 communities in Zambia and South Africa. Data are drawn from the seven intervention communities where immediate ART irrespective if CD4 count was offered from the trial-start in 2014. Median time from HIV-diagnosis to ART initiation reduced after 2 years of delivering the intervention from 10 to 6 months in both countries but varied by gender and community of residence. Social and health system realities impact decisions made by PLHIV about ART initiation. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10461-018-2335-7) contains supplementary material, which is available to authorized users.
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spelling pubmed-64589812019-05-03 Understanding the Time Needed to Link to Care and Start ART in Seven HPTN 071 (PopART) Study Communities in Zambia and South Africa Seeley, Janet Bond, Virginia Yang, Blia Floyd, Sian MacLeod, David Viljoen, Lario Phiri, Mwelwa Simuyaba, Melvin Hoddinott, Graeme Shanaube, Kwame Bwalya, Chiti de Villiers, Laing Jennings, Karen Mwanza, Margaret Schaap, Ab Dunbar, Rory Sabapathy, Kalpana Ayles, Helen Bock, Peter Hayes, Richard Fidler, Sarah AIDS Behav Original Paper To achieve UNAIDS 90:90:90 targets at population-level, knowledge of HIV status must be followed by timely linkage to care, initiation and maintenance of antiretroviral therapy (ART) for all people living with HIV (PLHIV). Interpreting quantitative patterns using qualitative data, we investigate time taken to link to care and initiate ART amongst individuals aware of their HIV-status in high HIV-prevalence urban communities in the HPTN 071 (PopART) study, a community-randomised trial of a combination HIV prevention package, including universal testing and treatment, in 21 communities in Zambia and South Africa. Data are drawn from the seven intervention communities where immediate ART irrespective if CD4 count was offered from the trial-start in 2014. Median time from HIV-diagnosis to ART initiation reduced after 2 years of delivering the intervention from 10 to 6 months in both countries but varied by gender and community of residence. Social and health system realities impact decisions made by PLHIV about ART initiation. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10461-018-2335-7) contains supplementary material, which is available to authorized users. Springer US 2018-11-10 2019 /pmc/articles/PMC6458981/ /pubmed/30415432 http://dx.doi.org/10.1007/s10461-018-2335-7 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Paper
Seeley, Janet
Bond, Virginia
Yang, Blia
Floyd, Sian
MacLeod, David
Viljoen, Lario
Phiri, Mwelwa
Simuyaba, Melvin
Hoddinott, Graeme
Shanaube, Kwame
Bwalya, Chiti
de Villiers, Laing
Jennings, Karen
Mwanza, Margaret
Schaap, Ab
Dunbar, Rory
Sabapathy, Kalpana
Ayles, Helen
Bock, Peter
Hayes, Richard
Fidler, Sarah
Understanding the Time Needed to Link to Care and Start ART in Seven HPTN 071 (PopART) Study Communities in Zambia and South Africa
title Understanding the Time Needed to Link to Care and Start ART in Seven HPTN 071 (PopART) Study Communities in Zambia and South Africa
title_full Understanding the Time Needed to Link to Care and Start ART in Seven HPTN 071 (PopART) Study Communities in Zambia and South Africa
title_fullStr Understanding the Time Needed to Link to Care and Start ART in Seven HPTN 071 (PopART) Study Communities in Zambia and South Africa
title_full_unstemmed Understanding the Time Needed to Link to Care and Start ART in Seven HPTN 071 (PopART) Study Communities in Zambia and South Africa
title_short Understanding the Time Needed to Link to Care and Start ART in Seven HPTN 071 (PopART) Study Communities in Zambia and South Africa
title_sort understanding the time needed to link to care and start art in seven hptn 071 (popart) study communities in zambia and south africa
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458981/
https://www.ncbi.nlm.nih.gov/pubmed/30415432
http://dx.doi.org/10.1007/s10461-018-2335-7
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