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Natamycin solid lipid nanoparticles – sustained ocular delivery system of higher corneal penetration against deep fungal keratitis: preparation and optimization

BACKGROUND: Fungal keratitis (FK) is a serious pathogenic condition usually associated with significant ocular morbidity. Natamycin (NAT) is the first-line and only medication approved by the Food and Drug Administration for the treatment of FK. However, NAT suffers from poor corneal penetration, wh...

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Detalles Bibliográficos
Autores principales: Khames, Ahmed, Khaleel, Mohammad A, El-Badawy, Mohamed F, El-Nezhawy, Ahmed O H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459158/
https://www.ncbi.nlm.nih.gov/pubmed/31040672
http://dx.doi.org/10.2147/IJN.S190502