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AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple-negative breast cancer
Triple-Negative Breast Cancer (TNBC) is an aggressive cancer subtype that is associated with a poor prognosis due to its propensity to form metastases. The receptor tyrosine kinase AXL plays a role in tumor cell dissemination and its expression in breast cancers correlates with poor patient survival...
Autores principales: | Goyette, Marie-Anne, Cusseddu, Rebecca, Elkholi, Islam, Abu-Thuraia, Afnan, El-Hachem, Nehme, Haibe-Kains, Benjamin, Gratton, Jean-Philippe, Côté, Jean-François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459349/ https://www.ncbi.nlm.nih.gov/pubmed/31007848 http://dx.doi.org/10.18632/oncotarget.26725 |
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