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CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor

The power of forward genetics in yeast is the foundation on which the field of autophagy research firmly stands. Complementary work on autophagy in higher eukaryotes has revealed both the deep conservation of this process, as well as novel mechanisms by which autophagy is regulated in the context of...

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Detalles Bibliográficos
Autores principales: Shoemaker, Christopher J., Huang, Tina Q., Weir, Nicholas R., Polyakov, Nicole J., Schultz, Sebastian W., Denic, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459555/
https://www.ncbi.nlm.nih.gov/pubmed/30933966
http://dx.doi.org/10.1371/journal.pbio.2007044