Contribution of Zinc-Dependent Delayed Calcium Influx via TRPC5 in Oxidative Neuronal Death and its Prevention by Novel TRPC Antagonist

Oxidative stress is a key mediator of neuronal death in acute brain injuries, such as epilepsy, trauma, and stroke. Although it is accompanied by diverse cellular changes, increases in levels of intracellular zinc ion (Zn(2+)) and calcium ion (Ca(2+)) may play a critical causative role in oxidative...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Sang Eun, Song, Ji Hoon, Hong, Chansik, Kim, Dong Eun, Sul, Jee-Won, Kim, Tae-Youn, Seo, Bo-Ra, So, Insuk, Kim, Sang-Yeob, Bae, Dong-Jun, Park, Mi-Ha, Lim, Hye Min, Baek, In-Jeoung, Riccio, Antonio, Lee, Joo-Yong, Shim, Woo Hyun, Park, Bumwoo, Koh, Jae-Young, Hwang, Jung Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459797/
https://www.ncbi.nlm.nih.gov/pubmed/30062674
http://dx.doi.org/10.1007/s12035-018-1258-7

Ejemplares similares

Ejemplares similares