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Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice

Harmful environmental stimuli during critical stages of development can profoundly affect behavior and susceptibility to diseases. Alzheimer disease (AD) is the most frequent neurodegenerative disease, and evidence suggest that inflammatory conditions act cumulatively, contributing to disease onset....

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Detalles Bibliográficos
Autores principales: Frost, Paula S., Barros-Aragão, Fernanda, da Silva, Rachel T., Venancio, Aline, Matias, Isadora, Lyra e Silva, Natalia M., Kincheski, Grasielle C., Pimentel-Coelho, Pedro M., De Felice, Fernanda G., Gomes, Flávia C. A., Ferreira, Sergio T., Figueiredo, Claudia P., Clarke, Julia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459845/
https://www.ncbi.nlm.nih.gov/pubmed/30975983
http://dx.doi.org/10.1038/s41419-019-1529-x