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Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice
Harmful environmental stimuli during critical stages of development can profoundly affect behavior and susceptibility to diseases. Alzheimer disease (AD) is the most frequent neurodegenerative disease, and evidence suggest that inflammatory conditions act cumulatively, contributing to disease onset....
Autores principales: | Frost, Paula S., Barros-Aragão, Fernanda, da Silva, Rachel T., Venancio, Aline, Matias, Isadora, Lyra e Silva, Natalia M., Kincheski, Grasielle C., Pimentel-Coelho, Pedro M., De Felice, Fernanda G., Gomes, Flávia C. A., Ferreira, Sergio T., Figueiredo, Claudia P., Clarke, Julia R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459845/ https://www.ncbi.nlm.nih.gov/pubmed/30975983 http://dx.doi.org/10.1038/s41419-019-1529-x |
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