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A sensitive scoring system for the longitudinal clinical evaluation and prediction of lethal disease outcomes in newborn mice

Neonatal animal models are increasingly employed in order to unravel age-specific disease mechanisms. Appropriate tools objectifying the clinical condition of murine neonates are lacking. In this study, we tested a scoring system specifically designed for newborn mice that relies on clinical observa...

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Detalles Bibliográficos
Autores principales: Fehlhaber, Beate, Heinemann, Anna S., Rübensam, Kathrin, Willers, Maike, Völlger, Lena, Pfeifer, Sandra, von Köckritz-Blickwede, Maren, Viemann, Dorothee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459866/
https://www.ncbi.nlm.nih.gov/pubmed/30976090
http://dx.doi.org/10.1038/s41598-019-42414-4