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A sensitive scoring system for the longitudinal clinical evaluation and prediction of lethal disease outcomes in newborn mice
Neonatal animal models are increasingly employed in order to unravel age-specific disease mechanisms. Appropriate tools objectifying the clinical condition of murine neonates are lacking. In this study, we tested a scoring system specifically designed for newborn mice that relies on clinical observa...
Autores principales: | Fehlhaber, Beate, Heinemann, Anna S., Rübensam, Kathrin, Willers, Maike, Völlger, Lena, Pfeifer, Sandra, von Köckritz-Blickwede, Maren, Viemann, Dorothee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459866/ https://www.ncbi.nlm.nih.gov/pubmed/30976090 http://dx.doi.org/10.1038/s41598-019-42414-4 |
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