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A Positive Causal Influence of IL-18 Levels on the Risk of T2DM: A Mendelian Randomization Study
A large number of clinical studies have shown that interleukin-18 (IL-18) plasma levels are positively correlated with the pathogenesis and development of type 2 diabetes mellitus (T2DM), but it remains unclear whether IL-18 causes T2DM, primarily due to the influence of reverse causality and residu...
Autores principales: | Zhuang, He, Han, Junwei, Cheng, Liang, Liu, Shu-Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459887/ https://www.ncbi.nlm.nih.gov/pubmed/31024619 http://dx.doi.org/10.3389/fgene.2019.00295 |
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