Mycobacteria-Specific Mono- and Polyfunctional CD4+ T Cell Profiles in Children With Latent and Active Tuberculosis: A Prospective Proof-of-Concept Study

Background: Current immune-based TB tests, including the tuberculin skin test (TST) and interferon-gamma release assays (IGRA), have significant limitations, including the inability to distinguish between latent TB infection (LTBI) and active TB. Few biomarkers with the potential to discriminate bet...

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Detalles Bibliográficos
Autores principales: Tebruegge, Marc, Ritz, Nicole, Donath, Susan, Dutta, Binita, Forbes, Benjamin, Clifford, Vanessa, Zufferey, Christel, De Rose, Robert, Robins-Browne, Roy M., Hanekom, Willem, Graham, Stephen M., Connell, Tom, Curtis, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459895/
https://www.ncbi.nlm.nih.gov/pubmed/31024518
http://dx.doi.org/10.3389/fimmu.2019.00431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459895/
https://www.ncbi.nlm.nih.gov/pubmed/31024518
http://dx.doi.org/10.3389/fimmu.2019.00431

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