Pleiotropic Clostridioides difficile Cyclophilin PpiB Controls Cysteine-Tolerance, Toxin Production, the Central Metabolism and Multiple Stress Responses

The Gram-positive pathogen Clostridioides difficile is the main bacterial agent of nosocomial antibiotic associated diarrhea. Bacterial peptidyl-prolyl-cis/trans-isomerases (PPIases) are well established modulators of virulence that influence the outcome of human pathologies during infections. Here,...

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Detalles Bibliográficos
Autores principales: Ünal, Can Murat, Karagöz, Mustafa Safa, Berges, Mareike, Priebe, Christina, Borrero de Acuña, José Manuel, Wissing, Josef, Jänsch, Lothar, Jahn, Dieter, Steinert, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459899/
https://www.ncbi.nlm.nih.gov/pubmed/31024308
http://dx.doi.org/10.3389/fphar.2019.00340

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