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Impaired cellular energy metabolism in cord blood macrophages contributes to abortive response toward inflammatory threats

Neonatal sepsis is characterized by hyperinflammation causing enhanced morbidity and mortality compared to adults. This suggests differences in the response towards invading threats. Here we investigate activated cord blood macrophages (CBMΦ) in comparison to adult macrophages (PBMΦ), indicating inc...

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Detalles Bibliográficos
Autores principales: Dreschers, Stephan, Ohl, Kim, Lehrke, Michael, Möllmann, Julia, Denecke, Bernd, Costa, Ivan, Vogl, Thomas, Viemann, Dorothee, Roth, Johannes, Orlikowsky, Thorsten, Tenbrock, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459909/
https://www.ncbi.nlm.nih.gov/pubmed/30976008
http://dx.doi.org/10.1038/s41467-019-09359-8