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Spatial Clustering of Receptors and Signaling Molecules Regulates NK Cell Response to Peptide Repertoire Changes
Natural Killer (NK) cell activation requires integration of inhibitory and activating signaling. Inhibitory signals are determined by members of the killer cell immunoglobulin-like receptor (KIR) family, which have major histocompatibility complex (MHC) class I ligands. Loss of this inhibitory signa...
Autores principales: | Mbiribindi, Berenice, Mukherjee, Sayak, Wellington, Dannielle, Das, Jayajit, Khakoo, Salim I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460049/ https://www.ncbi.nlm.nih.gov/pubmed/31024524 http://dx.doi.org/10.3389/fimmu.2019.00605 |
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