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Factor B and C4b2a Autoantibodies in C3 Glomerulopathy

C3 Glomerulopathy (C3G) is a renal disease mediated primarily by dysregulation of the alternative pathway of complement. Complement is the cornerstone of innate immunity. It targets infectious microbes for destruction, clears immune complexes, and apoptotic cells from the circulation, and augments t...

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Detalles Bibliográficos
Autores principales: Hauer, Jill J., Shao, Dingwu, Zhang, Yuzhou, Nester, Carla M., Smith, Richard J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460050/
https://www.ncbi.nlm.nih.gov/pubmed/31024533
http://dx.doi.org/10.3389/fimmu.2019.00668