In Vitro and In Vivo Detection of Drug-induced Apoptosis Using Annexin V-conjugated Ultrasmall Superparamagnetic Iron Oxide (USPIO): A Pilot Study

PURPOSE: To investigate the binding potential of newly developed Annexin V-conjugated ultrasmall superparamagnetic iron oxide (V-USPIO) for detection of drug-induced apoptosis in vitro and in vivo. METHODS: Apoptotic cells induced by camptothecin were incubated with or without Annexin V-USPIO at a c...

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Detalles Bibliográficos
Autores principales: Nishie, Akihiro, Togao, Osamu, Tamura, Chihiro, Yamato, Mayumi, Ichikawa, Kazuhiro, Nohara, Satoshi, Ito, Yoshio, Kato, Naoki, Yoshise, Satoshi, Honda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Magnetic Resonance in Medicine 2018
Materias:
Major Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460121/
https://www.ncbi.nlm.nih.gov/pubmed/30282879
http://dx.doi.org/10.2463/mrms.mp.2017-0157

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