Cell culture conditions affect the ability of high content imaging assay to detect drug-induced changes in cellular parameters in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are widely used for drug safety and efficacy testing with various techniques, including high content imaging (HCI). Upon drug treatment, a significant number of hiPSC-CMs grown in regular 96-well plates coated with fibronectin de...

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Detalles Bibliográficos
Autores principales: Balasubramanian, Bharathi, Belak, Vaclav, Verma, Isha, Prysiazhniuk, Yeva, Sannajust, Frederick, Trepakova, Elena S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460330/
https://www.ncbi.nlm.nih.gov/pubmed/31011540
http://dx.doi.org/10.1016/j.toxrep.2019.02.004

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