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Dabrafenib and Trametinib in BRAF Mutant Metastatic Conjunctival Melanoma
Conjunctival melanoma is a rare primary ocular tumor. So far, no standard treatment exists for metastatic disease. Similarly to cutaneous melanoma, up to 50% of conjunctival melanomas harbor BRAF mutations. The most common is represented by V600E. Combined therapy with BRAF and MEK inhibitors is app...
Autores principales: | Rossi, Ernesto, Maiorano, Brigida Anna, Pagliara, Monica Maria, Sammarco, Maria Grazia, Dosa, Tommaso, Martini, Maurizio, Rindi, Guido, Bria, Emilio, Blasi, Maria Antonietta, Tortora, Giampaolo, Schinzari, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460374/ https://www.ncbi.nlm.nih.gov/pubmed/31024839 http://dx.doi.org/10.3389/fonc.2019.00232 |
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