Cargando…

Machine-readable Yin–Yang imbalance: traditional Chinese medicine syndrome computer modeling based on three-dimensional noninvasive cardiac electrophysiology imaging

OBJECTIVES: The principal diagnostic methods of traditional Chinese medicine (TCM) are inspection, auscultation and olfaction, inquiry, and pulse-taking. Treatment by syndrome differentiation is likely to be subjective. This study was designed to provide a basic theory for TCM diagnosis and establis...

Descripción completa

Detalles Bibliográficos
Autores principales: Cen, Wei, Hoppe, Ralph, Sun, Aiwu, Ding, Hongyan, Gu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460602/
https://www.ncbi.nlm.nih.gov/pubmed/30832524
http://dx.doi.org/10.1177/0300060518824247
_version_ 1783410351239331840
author Cen, Wei
Hoppe, Ralph
Sun, Aiwu
Ding, Hongyan
Gu, Ning
author_facet Cen, Wei
Hoppe, Ralph
Sun, Aiwu
Ding, Hongyan
Gu, Ning
author_sort Cen, Wei
collection PubMed
description OBJECTIVES: The principal diagnostic methods of traditional Chinese medicine (TCM) are inspection, auscultation and olfaction, inquiry, and pulse-taking. Treatment by syndrome differentiation is likely to be subjective. This study was designed to provide a basic theory for TCM diagnosis and establish an objective means of evaluating the correctness of syndrome differentiation. METHODS: We herein provide the basic theory of TCM syndrome computer modeling based on a noninvasive cardiac electrophysiology imaging technique. Noninvasive cardiac electrophysiology imaging records the heart’s electrical activity from hundreds of electrodes on the patient’s torso surface and therefore provides much more information than 12-lead electrocardiography. Through mathematical reconstruction algorithm calculations, the reconstructed heart model is a machine-readable description of the underlying mathematical physics model that reveals the detailed three-dimensional (3D) electrophysiological activity of the heart. RESULTS: From part of the simulation results, the imaged 3D cardiac electrical source provides dynamic information regarding the heart’s electrical activity at any given location within the 3D myocardium. CONCLUSIONS: This noninvasive cardiac electrophysiology imaging method is suitable for translating TCM syndromes into a computable format of the underlying mathematical physics model to offer TCM diagnosis evidence-based standards for ensuring correct evaluation and rigorous, scientific data for demonstrating its efficacy.
format Online
Article
Text
id pubmed-6460602
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-64606022019-04-19 Machine-readable Yin–Yang imbalance: traditional Chinese medicine syndrome computer modeling based on three-dimensional noninvasive cardiac electrophysiology imaging Cen, Wei Hoppe, Ralph Sun, Aiwu Ding, Hongyan Gu, Ning J Int Med Res Clinical Research Reports OBJECTIVES: The principal diagnostic methods of traditional Chinese medicine (TCM) are inspection, auscultation and olfaction, inquiry, and pulse-taking. Treatment by syndrome differentiation is likely to be subjective. This study was designed to provide a basic theory for TCM diagnosis and establish an objective means of evaluating the correctness of syndrome differentiation. METHODS: We herein provide the basic theory of TCM syndrome computer modeling based on a noninvasive cardiac electrophysiology imaging technique. Noninvasive cardiac electrophysiology imaging records the heart’s electrical activity from hundreds of electrodes on the patient’s torso surface and therefore provides much more information than 12-lead electrocardiography. Through mathematical reconstruction algorithm calculations, the reconstructed heart model is a machine-readable description of the underlying mathematical physics model that reveals the detailed three-dimensional (3D) electrophysiological activity of the heart. RESULTS: From part of the simulation results, the imaged 3D cardiac electrical source provides dynamic information regarding the heart’s electrical activity at any given location within the 3D myocardium. CONCLUSIONS: This noninvasive cardiac electrophysiology imaging method is suitable for translating TCM syndromes into a computable format of the underlying mathematical physics model to offer TCM diagnosis evidence-based standards for ensuring correct evaluation and rigorous, scientific data for demonstrating its efficacy. SAGE Publications 2019-03-05 2019-04 /pmc/articles/PMC6460602/ /pubmed/30832524 http://dx.doi.org/10.1177/0300060518824247 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Clinical Research Reports
Cen, Wei
Hoppe, Ralph
Sun, Aiwu
Ding, Hongyan
Gu, Ning
Machine-readable Yin–Yang imbalance: traditional Chinese medicine syndrome computer modeling based on three-dimensional noninvasive cardiac electrophysiology imaging
title Machine-readable Yin–Yang imbalance: traditional Chinese medicine syndrome computer modeling based on three-dimensional noninvasive cardiac electrophysiology imaging
title_full Machine-readable Yin–Yang imbalance: traditional Chinese medicine syndrome computer modeling based on three-dimensional noninvasive cardiac electrophysiology imaging
title_fullStr Machine-readable Yin–Yang imbalance: traditional Chinese medicine syndrome computer modeling based on three-dimensional noninvasive cardiac electrophysiology imaging
title_full_unstemmed Machine-readable Yin–Yang imbalance: traditional Chinese medicine syndrome computer modeling based on three-dimensional noninvasive cardiac electrophysiology imaging
title_short Machine-readable Yin–Yang imbalance: traditional Chinese medicine syndrome computer modeling based on three-dimensional noninvasive cardiac electrophysiology imaging
title_sort machine-readable yin–yang imbalance: traditional chinese medicine syndrome computer modeling based on three-dimensional noninvasive cardiac electrophysiology imaging
topic Clinical Research Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460602/
https://www.ncbi.nlm.nih.gov/pubmed/30832524
http://dx.doi.org/10.1177/0300060518824247
work_keys_str_mv AT cenwei machinereadableyinyangimbalancetraditionalchinesemedicinesyndromecomputermodelingbasedonthreedimensionalnoninvasivecardiacelectrophysiologyimaging
AT hopperalph machinereadableyinyangimbalancetraditionalchinesemedicinesyndromecomputermodelingbasedonthreedimensionalnoninvasivecardiacelectrophysiologyimaging
AT sunaiwu machinereadableyinyangimbalancetraditionalchinesemedicinesyndromecomputermodelingbasedonthreedimensionalnoninvasivecardiacelectrophysiologyimaging
AT dinghongyan machinereadableyinyangimbalancetraditionalchinesemedicinesyndromecomputermodelingbasedonthreedimensionalnoninvasivecardiacelectrophysiologyimaging
AT guning machinereadableyinyangimbalancetraditionalchinesemedicinesyndromecomputermodelingbasedonthreedimensionalnoninvasivecardiacelectrophysiologyimaging