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MicroRNA-590-5p antagonizes the inhibitory effect of high glucose on osteoblast differentiation by suppressing Smad7 in MC3T3-E1 cells

OBJECTIVE: MicroRNA-590-5p (miR-590-5p) has been reported to stimulate osteoblast differentiation; however, its effect in diabetic osteoporosis remains unknown. This study investigated the effect of miR-590-5p on high glucose (HG)-suppressed osteoblast differentiation. METHODS: The effect of HG on M...

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Detalles Bibliográficos
Autores principales: Chen, Yinan, Sun, Changhui, Lu, Jiong, Zou, Ling, Hu, Minwei, Yang, Zeyu, Xu, Yaozeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460606/
https://www.ncbi.nlm.nih.gov/pubmed/30803283
http://dx.doi.org/10.1177/0300060519830212