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The index of prediction accuracy: an intuitive measure useful for evaluating risk prediction models

BACKGROUND: Many measures of prediction accuracy have been developed. However, the most popular ones in typical medical outcome prediction settings require additional investigation of calibration. METHODS: We show how rescaling the Brier score produces a measure that combines discrimination and cali...

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Autores principales: Kattan, Michael W., Gerds, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460739/
https://www.ncbi.nlm.nih.gov/pubmed/31093557
http://dx.doi.org/10.1186/s41512-018-0029-2
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author Kattan, Michael W.
Gerds, Thomas A.
author_facet Kattan, Michael W.
Gerds, Thomas A.
author_sort Kattan, Michael W.
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description BACKGROUND: Many measures of prediction accuracy have been developed. However, the most popular ones in typical medical outcome prediction settings require additional investigation of calibration. METHODS: We show how rescaling the Brier score produces a measure that combines discrimination and calibration in one value and improves interpretability by adjusting for a benchmark model. We have called this measure the index of prediction accuracy (IPA). The IPA permits a common interpretation across binary, time to event, and competing risk outcomes. We illustrate this measure using example datasets. RESULTS: The IPA is simple to compute, and example code is provided. The values of the IPA appear very interpretable. CONCLUSIONS: IPA should be a prominent measure reported in studies of medical prediction model performance. However, IPA is only a measure of average performance and, by default, does not measure the utility of a medical decision. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s41512-018-0029-2) contains supplementary material, which is available to authorized users.
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spelling pubmed-64607392019-05-15 The index of prediction accuracy: an intuitive measure useful for evaluating risk prediction models Kattan, Michael W. Gerds, Thomas A. Diagn Progn Res Methodology BACKGROUND: Many measures of prediction accuracy have been developed. However, the most popular ones in typical medical outcome prediction settings require additional investigation of calibration. METHODS: We show how rescaling the Brier score produces a measure that combines discrimination and calibration in one value and improves interpretability by adjusting for a benchmark model. We have called this measure the index of prediction accuracy (IPA). The IPA permits a common interpretation across binary, time to event, and competing risk outcomes. We illustrate this measure using example datasets. RESULTS: The IPA is simple to compute, and example code is provided. The values of the IPA appear very interpretable. CONCLUSIONS: IPA should be a prominent measure reported in studies of medical prediction model performance. However, IPA is only a measure of average performance and, by default, does not measure the utility of a medical decision. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s41512-018-0029-2) contains supplementary material, which is available to authorized users. BioMed Central 2018-05-04 /pmc/articles/PMC6460739/ /pubmed/31093557 http://dx.doi.org/10.1186/s41512-018-0029-2 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Methodology
Kattan, Michael W.
Gerds, Thomas A.
The index of prediction accuracy: an intuitive measure useful for evaluating risk prediction models
title The index of prediction accuracy: an intuitive measure useful for evaluating risk prediction models
title_full The index of prediction accuracy: an intuitive measure useful for evaluating risk prediction models
title_fullStr The index of prediction accuracy: an intuitive measure useful for evaluating risk prediction models
title_full_unstemmed The index of prediction accuracy: an intuitive measure useful for evaluating risk prediction models
title_short The index of prediction accuracy: an intuitive measure useful for evaluating risk prediction models
title_sort index of prediction accuracy: an intuitive measure useful for evaluating risk prediction models
topic Methodology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460739/
https://www.ncbi.nlm.nih.gov/pubmed/31093557
http://dx.doi.org/10.1186/s41512-018-0029-2
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