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Tailoring Corynebacterium glutamicum towards increased malonyl-CoA availability for efficient synthesis of the plant pentaketide noreugenin
BACKGROUND: In the last years, different biotechnologically relevant microorganisms have been engineered for the synthesis of plant polyphenols such as flavonoids and stilbenes. However, low intracellular availability of malonyl-CoA as essential precursor for most plant polyphenols of interest is re...
Autores principales: | Milke, Lars, Kallscheuer, Nicolai, Kappelmann, Jannick, Marienhagen, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460773/ https://www.ncbi.nlm.nih.gov/pubmed/30975146 http://dx.doi.org/10.1186/s12934-019-1117-x |
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