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Costimulatory and coinhibitory immune checkpoint receptors in head and neck cancer: unleashing immune responses through therapeutic combinations

Head and neck squamous cell carcinoma (HNSCC) represents a model of escape from anti-tumor immunity. The high frequency of p53 tumor suppressor loss in HNSCC leads to genomic instability and immune stimulation through the generation of neoantigens. However, the aggressive nature of HNSCC tumors and...

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Detalles Bibliográficos
Autores principales:	Davis, Ruth J., Ferris, Robert L., Schmitt, Nicole C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460794/ https://www.ncbi.nlm.nih.gov/pubmed/31093342 http://dx.doi.org/10.1186/s41199-016-0013-x

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