Lipoarabinomannan in sputum to detect bacterial load and treatment response in patients with pulmonary tuberculosis: Analytic validation and evaluation in two cohorts

BACKGROUND: Lipoarabinomannan (LAM) is a major antigen of Mycobacterium tuberculosis (MTB). In this report, we evaluated the ability of a novel immunoassay to measure concentrations of LAM in sputum as a biomarker of bacterial load prior to and during treatment in pulmonary tuberculosis (TB) patient...

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Detalles Bibliográficos
Autores principales: Kawasaki, Masanori, Echiverri, Carmenchu, Raymond, Lawrence, Cadena, Elizabeth, Reside, Evelyn, Gler, Maria Tarcela, Oda, Tetsuya, Ito, Ryuta, Higashiyama, Ryo, Katsuragi, Kiyonori, Liu, Yongge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461223/
https://www.ncbi.nlm.nih.gov/pubmed/30978194
http://dx.doi.org/10.1371/journal.pmed.1002780

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