MEK1/2 inhibitor U0126, but not nimodipine, reduces upregulation of cerebrovascular contractile receptors after subarachnoid haemorrhage in rats

Vascular pathophysiological changes after haemorrhagic stroke, such as phenotypic modulation of the cerebral arteries and cerebral vasospasms, are associated with delayed cerebral ischemia (DCI) and poor outcome. The only currently approved drug treatment shown to reduce the risk of DCI and improve...

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Detalles Bibliográficos
Autores principales: Christensen, Simon T., Johansson, Sara E., Radziwon-Balicka, Aneta, Warfvinge, Karin, Haanes, Kristian A., Edvinsson, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461292/
https://www.ncbi.nlm.nih.gov/pubmed/30978262
http://dx.doi.org/10.1371/journal.pone.0215398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461292/
https://www.ncbi.nlm.nih.gov/pubmed/30978262
http://dx.doi.org/10.1371/journal.pone.0215398

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