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Molecular determinants of WNT9b responsiveness in nephron progenitor cells

Primed nephron progenitor cells (NPCs) appear in metanephric mesenchyme by E11.5 and differentiate in response to the inductive WNT9b signal from the ureteric bud. However, the NPC WNT-receptor complex is unknown. We obtained M15 cells from E10.5 mesonephric mesenchyme and systematically analyzed co...

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Detalles Bibliográficos
Autores principales:	Dickinson, Kyle K., Hammond, Leah C., Karner, Courtney M., Hastie, Nicholas D., Carroll, Thomas J., Goodyer, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461349/ https://www.ncbi.nlm.nih.gov/pubmed/30978219 http://dx.doi.org/10.1371/journal.pone.0215139

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