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Vitamin K2-Dependent GGCX and MGP Are Required for Homeostatic Calcium Regulation of Sperm Maturation

A low-calcium microenvironment is essential for spermatozoa to mature in the epididymis; however, it remains unclear how dysregulation of epididymal luminal calcium is associated with male infertility. Using a warfarin-induced vitamin K2 deficiency rat model, we found that vitamin-K-dependent γ-glut...

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Detalles Bibliográficos
Autores principales:	Ma, He, Zhang, Bao Li, Liu, Bao Ying, Shi, Shuo, Gao, Da Yuan, Zhang, Tian Cheng, Shi, Hui Juan, Li, Zhen, Shum, Winnie Waichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461585/ https://www.ncbi.nlm.nih.gov/pubmed/30981116 http://dx.doi.org/10.1016/j.isci.2019.03.030

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