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Evidence for altered neurodevelopment and neurodegeneration in Wolfram syndrome using longitudinal morphometry
Wolfram syndrome is a rare disease caused by mutations in the WFS1 gene leading to symptoms in early to mid-childhood. Brain structural abnormalities are present even in young children, but it is not known when these abnormalities arise. Such information is critical in determining optimal outcome me...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461605/ https://www.ncbi.nlm.nih.gov/pubmed/30979932 http://dx.doi.org/10.1038/s41598-019-42447-9 |