Helicobacter pylori Vacuolating Cytotoxin A Causes Anorexia and Anxiety via Hypothalamic Urocortin 1 in Mice

Helicobacter pylori (Hp) infection is related to the pathogenesis of chronic gastric disorders and extragastric diseases. Here, we examined the anorexigenic and anxiogenic effects of Hp vacuolating cytotoxin A (VacA) through activation of hypothalamic urocortin1 (Ucn1). VacA was detected in the hypo...

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Detalles Bibliográficos
Autores principales: Suzuki, Hajime, Ataka, Koji, Asakawa, Akihiro, Cheng, Kai-Chun, Ushikai, Miharu, Iwai, Haruki, Yagi, Takakazu, Arai, Takeshi, Yahiro, Kinnosuke, Yamamoto, Katsuhiro, Yokoyama, Yoshito, Kojima, Masayasu, Yada, Toshihiko, Hirayama, Toshiya, Nakamura, Norifumi, Inui, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461611/
https://www.ncbi.nlm.nih.gov/pubmed/30979915
http://dx.doi.org/10.1038/s41598-019-42163-4

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