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ZFHX3 is indispensable for ERβ to inhibit cell proliferation via MYC downregulation in prostate cancer cells

Both estrogen receptor 2 (ESR2, also known as estrogen receptor beta (ERβ)) and the zinc-finger homeobox 3 (ZFHX3, also known as ATBF1 for AT motif-binding factor 1) modulate prostate development and suppress prostatic tumorigenesis in mice. ZFHX3 is integral to proper functions of ESR1 (i.e., estro...

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Detalles Bibliográficos
Autores principales: Hu, Qingxia, Zhang, Baotong, Chen, Rui, Fu, Changying, A, Jun, Fu, Xing, Li, Juan, Fu, Liya, Zhang, Zhiqian, Dong, Jin-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461672/
https://www.ncbi.nlm.nih.gov/pubmed/30979864
http://dx.doi.org/10.1038/s41389-019-0138-y

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