Sirt6-induced autophagy restricted TREM-1-mediated pyroptosis in ox-LDL-treated endothelial cells: relevance to prognostication of patients with acute myocardial infarction

Inflammation mediated by myeloid cells trigger receptors 1 (TREM-1) is important for atherosclerosis development, while sirtuin 6 (Sirt6) levels decrease in atheroscleoritc plaque. Here we demonstrate that oxidatively modified low density lipoprotein (ox-LDL)-treated endothelial cells (ECs) exhibite...

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Detalles Bibliográficos
Autores principales: Zi, Ye, Yi-An, Yao, Bing, Ji, Yan, Lai, Jing, Tong, Chun-Yu, Guan, Fan, Ping, Hao, Lin, Jia-Ni, Tang, Han-Jin, Hou, Fei, Chen, Xue-Bo, Liu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461678/
https://www.ncbi.nlm.nih.gov/pubmed/30993014
http://dx.doi.org/10.1038/s41420-019-0168-4

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