Cargando…

Bisacylphosphane oxides as photo-latent cytotoxic agents and potential photo-latent anticancer drugs

Bisacylphosphane oxides (BAPOs) are established as photoinitiators for industrial applications. Light irradiation leads to their photolysis, producing radicals. Radical species induce oxidative stress in cells and may cause cell death. Hence, BAPOs may be suitable as photolatent cytotoxic agents, bu...

Descripción completa

Detalles Bibliográficos
Autores principales: Beil, Andreas, Steudel, Friederike A., Bräuchle, Christoph, Grützmacher, Hansjörg, Möckl, Leonhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461680/
https://www.ncbi.nlm.nih.gov/pubmed/30979960
http://dx.doi.org/10.1038/s41598-019-42026-y