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Physical activity and subsequent risk of kidney, bladder and upper urinary tract cancer in the Japanese population: the Japan Public Health Centre-based Prospective Study
BACKGROUND: Although physical activity has been reported as a protective factor for kidney and bladder cancer in epidemiological studies, it is not clear. METHODS: In a population-based prospective study of 76,795 Japanese aged 45–74 years, participants were evaluated physical activity by self-admin...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461777/ https://www.ncbi.nlm.nih.gov/pubmed/30745583 http://dx.doi.org/10.1038/s41416-019-0392-y |
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author | Ihira, Hikaru Sawada, Norie Yamaji, Taiki Goto, Atsushi Shimazu, Taichi Inoue, Manami Iwasaki, Motoki Tsugane, Shoichiro |
author_facet | Ihira, Hikaru Sawada, Norie Yamaji, Taiki Goto, Atsushi Shimazu, Taichi Inoue, Manami Iwasaki, Motoki Tsugane, Shoichiro |
author_sort | Ihira, Hikaru |
collection | PubMed |
description | BACKGROUND: Although physical activity has been reported as a protective factor for kidney and bladder cancer in epidemiological studies, it is not clear. METHODS: In a population-based prospective study of 76,795 Japanese aged 45–74 years, participants were evaluated physical activity by self-administered questionnaire. Hazard ratios (HRs) and 95% confidence intervals (CIs) of the risk of urological cancer were calculated by the Cox proportional hazards models. RESULTS: During the 15.1-year follow-up, 202 kidney, 373 bladder and 83 upper urinary tract cancer cases were identified. Physical activity was not significantly associated with kidney, bladder and upper urinary tract cancer risks, with multivariate HRs in the highest versus lowest group of 1.05 (95% CI: 0.74–1.49), 1.06 (95% CI: 0.81–1.39) and 0.80 (95% CI: 0.48–1.35), respectively. CONCLUSIONS: Physical activity was not associated with the risk of urological cancer in the Japanese population. |
format | Online Article Text |
id | pubmed-6461777 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-64617772020-02-12 Physical activity and subsequent risk of kidney, bladder and upper urinary tract cancer in the Japanese population: the Japan Public Health Centre-based Prospective Study Ihira, Hikaru Sawada, Norie Yamaji, Taiki Goto, Atsushi Shimazu, Taichi Inoue, Manami Iwasaki, Motoki Tsugane, Shoichiro Br J Cancer Article BACKGROUND: Although physical activity has been reported as a protective factor for kidney and bladder cancer in epidemiological studies, it is not clear. METHODS: In a population-based prospective study of 76,795 Japanese aged 45–74 years, participants were evaluated physical activity by self-administered questionnaire. Hazard ratios (HRs) and 95% confidence intervals (CIs) of the risk of urological cancer were calculated by the Cox proportional hazards models. RESULTS: During the 15.1-year follow-up, 202 kidney, 373 bladder and 83 upper urinary tract cancer cases were identified. Physical activity was not significantly associated with kidney, bladder and upper urinary tract cancer risks, with multivariate HRs in the highest versus lowest group of 1.05 (95% CI: 0.74–1.49), 1.06 (95% CI: 0.81–1.39) and 0.80 (95% CI: 0.48–1.35), respectively. CONCLUSIONS: Physical activity was not associated with the risk of urological cancer in the Japanese population. Nature Publishing Group UK 2019-02-12 2019-03-05 /pmc/articles/PMC6461777/ /pubmed/30745583 http://dx.doi.org/10.1038/s41416-019-0392-y Text en © Cancer Research UK 2019 https://creativecommons.org/licenses/by/4.0/Note: This work is published under the standard license to publish agreement. After 12 months the work will become freely available and the license terms will switch toa Creative Commons Attribution 4.0 International (CC BY 4.0). |
spellingShingle | Article Ihira, Hikaru Sawada, Norie Yamaji, Taiki Goto, Atsushi Shimazu, Taichi Inoue, Manami Iwasaki, Motoki Tsugane, Shoichiro Physical activity and subsequent risk of kidney, bladder and upper urinary tract cancer in the Japanese population: the Japan Public Health Centre-based Prospective Study |
title | Physical activity and subsequent risk of kidney, bladder and upper urinary tract cancer in the Japanese population: the Japan Public Health Centre-based Prospective Study |
title_full | Physical activity and subsequent risk of kidney, bladder and upper urinary tract cancer in the Japanese population: the Japan Public Health Centre-based Prospective Study |
title_fullStr | Physical activity and subsequent risk of kidney, bladder and upper urinary tract cancer in the Japanese population: the Japan Public Health Centre-based Prospective Study |
title_full_unstemmed | Physical activity and subsequent risk of kidney, bladder and upper urinary tract cancer in the Japanese population: the Japan Public Health Centre-based Prospective Study |
title_short | Physical activity and subsequent risk of kidney, bladder and upper urinary tract cancer in the Japanese population: the Japan Public Health Centre-based Prospective Study |
title_sort | physical activity and subsequent risk of kidney, bladder and upper urinary tract cancer in the japanese population: the japan public health centre-based prospective study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461777/ https://www.ncbi.nlm.nih.gov/pubmed/30745583 http://dx.doi.org/10.1038/s41416-019-0392-y |
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