TRIM47 is up-regulated in colorectal cancer, promoting ubiquitination and degradation of SMAD4

BACKGROUND: Tripartite motif 47 (TRIM47), a member of the TRIM family proteins, plays a key role in many types of cancers including colorectal cancer (CRC). We found that levels of TRIM47 mRNA and protein were increased significantly in colorectal tumors compared with nontumor tissues and the increa...

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Detalles Bibliográficos
Autores principales: Liang, Qian, Tang, Chaotao, Tang, Mingyu, Zhang, Qingwei, Gao, Yunjie, Ge, Zhizheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461818/
https://www.ncbi.nlm.nih.gov/pubmed/30979374
http://dx.doi.org/10.1186/s13046-019-1143-x

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