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Dysregulation of sonic hedgehog pathway and pericytes in the brain after lentiviral infection
BACKGROUND: Impairment of the blood–brain barrier (BBB) has been associated with cognitive decline in many CNS diseases, including HIV-associated neurocognitive disorders (HAND). Recent research suggests an important role for the Sonic hedgehog (Shh) signaling pathway in the maintenance of BBB integ...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461821/ https://www.ncbi.nlm.nih.gov/pubmed/30981282 http://dx.doi.org/10.1186/s12974-019-1463-y |