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Dysregulation of sonic hedgehog pathway and pericytes in the brain after lentiviral infection

BACKGROUND: Impairment of the blood–brain barrier (BBB) has been associated with cognitive decline in many CNS diseases, including HIV-associated neurocognitive disorders (HAND). Recent research suggests an important role for the Sonic hedgehog (Shh) signaling pathway in the maintenance of BBB integ...

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Detalles Bibliográficos
Autores principales: Bohannon, Diana G., Ko, Allen, Filipowicz, Adam R., Kuroda, Marcelo J., Kim, Woong-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461821/
https://www.ncbi.nlm.nih.gov/pubmed/30981282
http://dx.doi.org/10.1186/s12974-019-1463-y

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