High hepatic expression of PDK4 improves survival upon multimodal treatment of colorectal liver metastases

BACKGROUND: Patients with borderline resectable colorectal liver metastases (CRLM) frequently receive neoadjuvant chemotherapy (NC) to reduce tumour burden, thus making surgical resection feasible. Even though NC can induce severe liver injury, most studies investigating tissue-based prognostic mark...

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Detalles Bibliográficos
Autores principales: Strowitzki, Moritz J., Radhakrishnan, Praveen, Pavicevic, Sandra, Scheer, Jana, Kimmer, Gwendolyn, Ritter, Alina S., Tuffs, Christopher, Volz, Claudia, Vondran, Florian, Harnoss, Jonathan M., Klose, Johannes, Schmidt, Thomas, Schneider, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461828/
https://www.ncbi.nlm.nih.gov/pubmed/30808993
http://dx.doi.org/10.1038/s41416-019-0406-9

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