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Structures of the human spliceosomes before and after release of the ligated exon

Pre-mRNA splicing is executed by the spliceosome, which has eight major functional states each with distinct composition. Five of these eight human spliceosomal complexes, all preceding exon ligation, have been structurally characterized. In this study, we report the cryo-electron microscopy structu...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiaofeng, Zhan, Xiechao, Yan, Chuangye, Zhang, Wenyu, Liu, Dongliang, Lei, Jianlin, Shi, Yigong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461851/ https://www.ncbi.nlm.nih.gov/pubmed/30728453 http://dx.doi.org/10.1038/s41422-019-0143-x

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